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DESCRIPTION OF DRUG XYLOCAINE

Сontents:
Xylocaine, instruction manual
Pharmacological action of xylocaine
Indications for admission xylocaine
Dosing regimen xylocaine
Interaction xylocaine
Side effects xylocaine
Contraindications when using xylocaine

 

Xylocaine, instruction manual

International name. Lidocain. Structure and Composition Xylocain. Active ingredient - lidocaine hydrochloride. Solution 1% 20mlv ampoules of 5 pcs. in package. Structure 2% -20 ml in 5 pcs. in container. Fluid 2% - 2 ml in 100 pieces box. Xylocain-adrenaline 2% -2 ml in 100 pcs. in package. Powder for 0.5%, 1% and 2% solutions Xylocain with epinephrine 1:200,000 in breeding.

Pharmacological action of xylocaine

antiarrhythmic . Does not change emotsianalno sinoatrial node , has little effect on the conductivity and contractility . When administered intravenously, acts fast and little (13-25 minutes). Mechanism of local anesthetic effect is to stabilize the neuronal membrane , reducing its permeability to sodium ions , thus preventing potential action and conduction of impulses . Instant hydrolyzed under mildly alkaline Wednesday fabrics and after a short latency period is valid for 50-80 minutes. When inflammation (tissue acidosis) anesthetic activity decreases. Effective with all kinds of local anesthesia. Dilates blood vessels . Not irritating to the tkani.Dostatochno soon is absorbed by the mucous membranes of the upper respiratory tract or oral cavity. Stable concentration in the blood is established through 4-5 hours with continuous intravenous administration. Easy passes passing gistogematicalkie barriers, including GEB. Crosses the placenta . Instant and almost completely metabolized in the liver .

Indications for admission xylocaine

Terminal, infiltration, conduction, spinal (epidural) anesthesia in surgery, ophthalmology, dentistry, otorhinolaryngology. Lidocaine do for blockade of peripheral nerves and ganglia. Ventricular arrhythmias form (tachycardia and ventricular premature beats) and mostly to prevent ventricular fibrillation in severe stage of myocardial infarction.

Dosing regimen xylocaine

Infiltration anesthesia for total 0.25% the solution should not exceed 1000 ml and 0.5% solution - 500ml. For conduction anesthesia is administered to 50ml 0.5-1-2% solution. As the antiarrhythmic agents are administered intravenously 60 mg over 3-4 minutes, followed by intravenous infusion of the solution containing 2 mg | ml of lidocaine at a rate 4 mg | min.

Interaction xylocaine

Beta-blockers increase the likelihood of growth bradycardia and hypotension.

Side effects xylocaine

Lidocaine is usually better, but it may idiosyncrasy. In case of overdose can occur weakness, nausea, irritability, visual disturbances, tremors, convulsions and even simple breathing. With rapid intravenous lidocaine may fall blood pressure up to the collapse.

Contraindications when using xylocaine

Master sensitivity local anesthetics of the amide site.

 

Сontents:
Xylocaine, instruction manual.
Pharmacological action of xylocaine
Indications for admission xylocaine
Dosing regimen xylocaine
Interaction xylocaine
Side effects xylocaine
Contraindications when using xylocaine

 

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